Bundles called lipoproteins carry cholesterol throughout the body. Cholesterol metabolism 1. At normal levels, it is an essential substance for the body. Your body needs some cholesterol to make hormones, vitamin D, and substances that help you digest foods. As the body requires cholesterol, it may be secreted by the liver. Cholesterol content in the bloodstream is regulated by the liver. Disturbances in cholesterol metabolism cause various diseases. Cholesterol has a bad reputation, thanks to its well-known role in promoting heart disease. CHOLESTEROL PRESENTED BY:-SILENT KILLERS 2. Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Excess cholesterol in the bloodstream is a key contributor to artery-clogging plaque, which can accumulate and set the stage for a heart attack. However, the role of cholesterol … However, if concentrations in the blood get too high, it … Hypercholesterolemia. A total cholesterol score of 200 mg/dL or lower is considered optimal. Metabolic disease - Metabolic disease - Disorders of lipid metabolism: Lipids are large, water-insoluble molecules that have a variety of biological functions, including storing energy and serving as components of cellular membranes and lipoproteins. After a meal, cholesterol in the diet is absorbed from the small intestine and metabolized and stored in the liver. The science behind the GOOD and BAD cholesterol. Cholesterol metabolism : Cholesterol is readily oxidized to form Oxysterols. The American Heart Association explains how cholesterol affects the heart. Cholesterol is both good and bad. Your body makes all the cholesterol it needs. A cholesterol test will measure the total cholesterol in your blood, and your total cholesterol levels are made up of a combination of your LDL, HDL, and VLDL (very low density lipoprotein, another "bad" cholesterol) levels. Its overall effect is … The excess cholesterol produced in this way activates acetyl-CoA cholesterol acyl-transferase (ACAT), which re-esterifies cholesterol into cholesterol esters that can be deposited as lipid droplets or mobilized again to where it is needed. Learn about prevention and treatment of high cholesterol, triglycerides, ldl, hdl, athersclerosis, arteriosclerosis, hypercholesterolemia, bad cholesterol, reducing cholesterol, cholesterol screening, cholesterol tracker, recipes and preventing high cholesterol. Cholesterol can be oxidized in three ways as follows : Autooxidation, Secondary Oxidation and Cholesterol-metabolizing Enzyme Oxidation. Flow of Presentation What is Lipids – Rajesh Conversion of VLDL to LDL – Kuldip Fatty acid oxidation – Zalak Oxidation of odd carbon - Pravin Ketone Bodies – Sachin Metabolism of Cholesterol & functions – Kishore Cholesterol Biosynthesis – Gulab Regulation of Cholesterol – Aadesh Degradation of Cholesterol … What is cholesterol? 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